| Date | Location | Result | |
| Nov 20, 2010 | Tigerville, SC | North Greenville 42, Campbellsville 16 | |
| Nov 13, 2010 | Montgomery, WV | Campbellsville 56, West Virginia Tech 35 | |
| Nov 6, 2010 | Wise, VA | Campbellsville 45, Virginia-Wise 42 | |
| Oct 23, 2010 | Campbellsville, KY | Campbellsville 22, Faulkner College 21 | |
| Oct 16, 2010 | Williamsburg, KY | U of Cumberlands 34, Campbellsville 28 | |
| Oct 7, 2010 | Campbellsville, KY | Georgetown College 52, Campbellsville 21 | |
| Oct 2, 2010 | Pikeville, KY | Campbellsville 62, Pikeville College 17 | |
| Sep 25, 2010 | Campbellsville, KY | Campbellsville 48, Lindsey Wilson 30 | |
| Sep 18, 2010 | Campbellsville, KY | Wisconsin-Whitewater 37, Campbellsville 7 | |
| Sep 11, 2010 | Lebanon, TN | Cumberland U. 33, Campbellsville 21 | |
| Sep 4, 2010 | Barbourville, KY | Campbellsville 47, Union College 36 | |
| Aug 28, 2010 | Campbellsville, KY | Campbellsville 34, Kentucky Christian 7 |